Draw out or create a flow chart of the movement of electrons and H+ through the photosystems and electron transport.

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Assignment Question

Draw out or create a flow chart of the movement of electrons and H+ through the photosystems and electron transport. (detailed) Draw out or create a flow chart of cellular respiration using fatty acids as the starting point rather than glucose. (detailed)

Assignment Answer


Photosynthesis and cellular respiration are fundamental processes in biology, playing a pivotal role in energy conversion and the sustenance of life on Earth. Photosynthesis occurs in plants and certain microorganisms, capturing solar energy and converting it into chemical energy in the form of glucose. In contrast, cellular respiration is the process through which cells generate energy by breaking down organic molecules like glucose or, as we will explore in detail, fatty acids. In this essay, we will delve into the intricate details of the movement of electrons and protons (H+) through the photosystems during photosynthesis and create a comprehensive flowchart for cellular respiration, focusing on fatty acids as the starting point. By understanding these processes, we gain insights into the remarkable intricacies of energy transfer and the interconnectedness of life on our planet.

I. Photosynthesis and Electron Flow:

Photosynthesis is the process by which plants, algae, and some bacteria convert light energy into chemical energy in the form of glucose. At the heart of this process are the photosystems, specifically Photosystem I (PSI) and Photosystem II (PSII), which play a crucial role in the movement of electrons and H+ ions. In PSII, chlorophyll molecules absorb photons, exciting electrons, which are then transferred to a primary electron acceptor (PEA) (Blankenship, 2017). The excited electrons leave a “hole” in the chlorophyll, which is filled by extracting electrons from water molecules, leading to the release of oxygen gas (O2) and protons (H+) (Nelson & Yocum, 2006). This complex electron movement ensures the continuity of electron flow.

Subsequently, electrons are transported through a series of carriers in the thylakoid membrane, known as the electron transport chain (ETC). Plastoquinone, cytochrome b6f complex, and plastocyanin are involved in this chain, facilitating the transfer of electrons between them (Nelson & Ben-Shem, 2005). Protons (H+) are pumped into the thylakoid lumen, creating a proton gradient that serves as a potential energy source for ATP synthesis. ATP synthase, embedded in the thylakoid membrane, allows protons to flow back into the stroma while catalyzing ATP formation (McDermott et al., 1996). This process is a pivotal part of the photosynthetic electron transport chain. In PSI, another set of chlorophyll molecules captures photons, exciting electrons once again, and these electrons are transferred to another primary electron acceptor (Blankenship, 2017). Meanwhile, the electrons lost from PSI are replaced by those coming from PSII through a pathway involving ferredoxin and ferredoxin-NADP+ reductase (FNR) (Nelson & Ben-Shem, 2005). NADP+ molecules are reduced to NADPH, storing the energy needed for the subsequent dark reactions of photosynthesis. Overall, the movement of electrons and H+ ions through the photosystems and the electron transport chain in photosynthesis is a highly coordinated process that results in the generation of ATP and NADPH, essential molecules for the synthesis of glucose.

II. Cellular Respiration with Fatty Acids:

Cellular respiration is a complex process that occurs in all living cells, allowing them to extract energy from organic molecules. While glucose is the primary substrate for respiration, fatty acids can also serve as an energy source. Here, we will outline a detailed flowchart of cellular respiration starting with fatty acids.

Beta-Oxidation of Fatty Acids: Fatty acids are first transported into the mitochondria, where they undergo beta-oxidation. During this process, fatty acids are broken down into two-carbon units in a cyclical manner, releasing NADH and FADH2 as electron carriers (Houten & Wanders, 2010).

Krebs Cycle (Citric Acid Cycle): The two-carbon units, in the form of acetyl-CoA, enter the Krebs cycle. Here, acetyl-CoA is oxidized, leading to the production of NADH and FADH2. Additionally, the cycle generates ATP and carbon dioxide as byproducts (Berg et al., 2002).

Electron Transport Chain: The NADH and FADH2 generated in the previous steps enter the electron transport chain located in the inner mitochondrial membrane. Similar to photosynthesis, this chain consists of a series of protein complexes that facilitate the movement of electrons. Electrons pass through complexes I, III, and IV, and in the process, protons are pumped into the intermembrane space.

ATP Synthesis: The proton gradient generated by the electron transport chain creates a proton motive force, which drives ATP synthesis through ATP synthase, akin to photosynthesis. This is known as oxidative phosphorylation (Nicholls & Ferguson, 2013).

Final Electron Acceptor: Unlike photosynthesis, where the final electron acceptor is NADP+, in cellular respiration, the final electron acceptor is oxygen. Oxygen combines with electrons and protons to form water (H2O), thereby completing the electron transport chain (Brand, 2016).

III. Fatty Acid Transport and Activation:

Fatty Acid Uptake: Before fatty acids can be used for cellular respiration, they must be transported into cells. Cells take up fatty acids from the bloodstream using transport proteins, such as fatty acid translocase (FAT/CD36), and fatty acid binding proteins (FABPs) (Stremmel et al., 2001).

Activation to Acyl-CoA: Once inside the cell, fatty acids are activated by attaching a coenzyme A (CoA) molecule to form fatty acyl-CoA. This activation step occurs in the cytoplasm and is catalyzed by acyl-CoA synthetases (Watkins, 2008).

IV. Regulation of Fatty Acid Respiration:

Regulation of Beta-Oxidation: The rate of beta-oxidation of fatty acids is tightly regulated. Enzymes involved in beta-oxidation are often controlled by allosteric regulation and post-translational modifications. For instance, malonyl-CoA inhibits carnitine palmitoyltransferase I (CPT-1), preventing fatty acid entry into the mitochondria (McGarry & Brown, 1997).

Hormonal Control: Hormones such as insulin and glucagon play a significant role in regulating fatty acid metabolism. Insulin promotes fatty acid synthesis and storage, while glucagon stimulates the release of stored fatty acids for energy production (Brown & Goldstein, 2008).

V. Yield of ATP from Fatty Acid Respiration:

Energy Output: Fatty acid respiration yields a significant amount of ATP. For each cycle of beta-oxidation, one acetyl-CoA molecule is generated, which can enter the Krebs cycle to produce 3 NADH, 1 FADH2, and 1 ATP (Watkins, 2008).

Comparison to Glucose: Fatty acid metabolism generates more ATP per carbon atom than glucose. This is why the oxidation of fats is an efficient way to store and release energy for prolonged activities, such as endurance exercise (Hoppeler & Flück, 2003).

VI. Role of Fatty Acid Respiration in Health and Disease:

Role in Obesity: An imbalance in fatty acid metabolism can contribute to obesity. Excessive intake of fatty acids combined with a sedentary lifestyle can lead to an accumulation of fat in adipose tissue, contributing to obesity (Schwartz et al., 2003).

Fatty Acid Oxidation Disorders: Inborn errors of metabolism can affect fatty acid oxidation. Disorders such as medium-chain acyl-CoA dehydrogenase deficiency (MCADD) can lead to the inability to properly metabolize fatty acids, resulting in a risk of hypoglycemia and other health issues (Wanders & Ruiter, 2011).


In this essay, we have explored the intricate details of the movement of electrons and H+ ions through the photosystems during photosynthesis and created a comprehensive flowchart for cellular respiration, focusing on fatty acids as the starting point. These two processes are fundamental for life, as they demonstrate how energy is harnessed and transferred within living organisms. The understanding of these processes helps us appreciate the remarkable complexities of nature and the interconnectedness of all life forms on our planet.


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